• DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival 

      Pedersen, Christine Aaserød; Cao, Maria Dung; Fleischer, Thomas; Rye, Morten Beck; Knappskog, Stian; Eikesdal, Hans Petter; Lønning, Per Eystein; Tost, Jörg; Kristensen, Vessela N.; Tessem, May-Britt; Giskeødegård, Guro F.; Bathen, Tone Frost (Peer reviewed; Journal article, 2022)
      Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ...
    • From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients 

      Tune, Benedicte Grebstad; Sareen, Heena; Powter, Branka; Kahana-Edwin, Smadar; Cooper, Adam; Koh, Eng-Siew; Lee, Cheok S.; Po, Joseph W.; McCowage, Geoff; Dexter, Mark; Cain, Lucy; O’Neill, Geraldine; Prior, Victoria; Karpelowsky, Jonathan; Tsoli, Maria; Baumbusch, Lars Oliver; Ziegler, David; Roberts, Tara L.; DeSouza, Paul; Becker, Therese M.; Ma, Yafeng (Peer reviewed; Journal article, 2023)
      Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by HIST1H3B and HIST1H3C) and H3.3 (encoded by H3F3A), are mainly associated ...
    • Incidence of cancer in patients with ulcerative colitis 30 years after diagnosis (the IBSEN study) 

      Follin-Arbelet, Benoit; Småstuen, Milada Cvancarova; Hovde, Øistein; Jelsness-Jørgensen, Lars-Petter; Moum, Bjørn Allan (Peer reviewed; Journal article, 2023-06-20)
      Objectives Patients with ulcerative colitis (UC) have shown an increased risk for colorectal cancer, hepatobiliary, hematologic, and skin cancers, but updated long-term data is needed. This study aimed to estimate the ...
    • Malignant skin melanoma detection using image augmentation by oversampling in nonlinear lower-dimensional embedding manifold 

      Abayomi-Alli, Olusola Oluwakemi; Damaševičius, Robertas; Misra, Sanjay; Maskeliunas, Rytis; Abayomi-Alli, Adebayo (Journal article, 2021)
      The continuous rise in skin cancer cases, especially in malignant melanoma, has resulted in a high mortality rate of the affected patients due to late detection. Some challenges affecting the success of skin cancer detection ...
    • Medical Internet-of-Things Based Breast Cancer Diagnosis Using Hyperparameter-Optimized Neural Networks 

      Ogundokun, Roseline Oluwaseun; Misra, Sanjay; Douglas, Mychal; Damaševičius, Robertas; Maskeliunas, Rytis (Peer reviewed; Journal article, 2022)
      In today’s healthcare setting, the accurate and timely diagnosis of breast cancer is critical for recovery and treatment in the early stages. In recent years, the Internet of Things (IoT) has experienced a transformation ...
    • Risk of Cancer in Patients With Crohn's Disease 30 Years After Diagnosis (the IBSEN Study) 

      Follin-Arbelet, Benoit; Småstuen, Milada Cvancarova; Hovde, Øistein; Jelsness-Jørgensen, Lars-Petter; Moum, Bjørn Allan (Journal article, 2023)
      Background: Patients with Crohn's disease (CD) are most often diagnosed as young adults; therefore, long-term studies are needed to assess the risk of cancer over their lifetime. Thus, the aims of the present study were ...