dc.contributor.author | Østby, Runa Berg | |
dc.contributor.author | Didriksen, Terje | |
dc.contributor.author | Antonsen, Simen Gjelseth | |
dc.contributor.author | Nicolaisen, Steinar Sollien | |
dc.contributor.author | Stenstrøm, Yngve H. | |
dc.date.accessioned | 2021-02-16T18:52:53Z | |
dc.date.available | 2021-02-16T18:52:53Z | |
dc.date.created | 2020-05-19T23:17:41Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Molecules. 2020, 25 (10):2364. | en_US |
dc.identifier.issn | 1420-3049 | |
dc.identifier.uri | https://hdl.handle.net/11250/2728528 | |
dc.description.abstract | Dibromocyclopropanations are conventionally done by addition of dibromocarbene to alkenes under phase-transfer conditions in batch reactions using a strong base (50% NaOH (aq)), vigorous stirring and long reaction times. We have shown that cyclopropanation of unsaturated alcohols can be done under ambient conditions using continuous flow chemistry with 40% (w/w) NaOH (aq) as the base. The reactions were generally rapid; the yields were comparable to yields reported in the literature for the conventional batch reaction | en_US |
dc.language.iso | eng | en_US |
dc.publisher | MDPI | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.subject | dibromocyclopropanation | en_US |
dc.subject | CHBr3 | en_US |
dc.subject | Makosza reaction | en_US |
dc.subject | phase-transfer catalysis | en_US |
dc.subject | flow chemistry | en_US |
dc.subject | unsaturated alcohols | en_US |
dc.title | Two-phase dibromocyclopropanation of unsaturated alcohols using flow chemistry | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | © 2020 by the authors. | |
dc.subject.nsi | VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440 | en_US |
dc.source.volume | 25 | en_US |
dc.source.journal | Molecules | en_US |
dc.source.issue | 10 | en_US |
dc.identifier.doi | 10.3390/molecules25102364 | |
dc.identifier.cristin | 1811816 | |
dc.source.articlenumber | 2364 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |