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dc.contributor.authorStafne, Signe Nilssen
dc.contributor.authorMørkved, Siv
dc.contributor.authorGustafsson, Miriam Katarina
dc.contributor.authorSyversen, Unni
dc.contributor.authorStunes, Astrid Kamilla
dc.contributor.authorSalvesen, Kjell Å
dc.contributor.authorJohannessen, Hege Hølmo
dc.identifier.citationBJOG: An International Journal of Obstetrics and Gynaecology. 2020, 127 (13), 1704-1711.en_US
dc.description.abstractObjective To assess the association between levels of vitamin D and urinary incontinence (UI) in pregnancy. Design A cross‐sectional study. Secondary analysis of a randomised controlled trial. Setting Two university hospitals in Norway. Population A total of 851 healthy, pregnant women >18 years in gestational weeks 18–22 with a singleton live fetus. Methods Data on UI were collected from a questionnaire at inclusion and serum analysis of 25‐hydroxy vitamin D (25(OH)D) was performed. Univariable and multivariable logistic regression analyses were applied to study associations between exposure and outcomes. Main outcome measures Prevalence of self‐reported UI, stress (SUI) and urge (UUI) or mixed UI. Results In total, 230/851 (27%) of the participants were vitamin D insufficient (25(OH)D <50 nmol/l) and 42% reported to have any UI. Women with 25(OH)D <50 nmol/l were more likely to report any UI (P = 0.03) and SUI (P < 0.01) compared with women with 25(OH)D ≥50 nmol/l. In a univariable logistic regression analysis, serum levels of 25(OH)D <50 nmol/l was associated with increased risk of any UI (odds ratio [OR] 1.5 with 95% CI 1.0–2.1), SUI only (OR 1.7, 95% CI 1.2–2.4), but not mixed UI or UUI only (OR 0.8, 95% CI 0.5–1.5). In a multivariable logistic regression model, serum levels of 25(OH)D <50 nmol/l were associated with a higher risk of experiencing SUI only (OR 1.5, 95% CI 1.1–2.2). Conclusions Serum 25(OH)D <50 nmol/l was associated with increased risk of any UI, and SUI in particular.en_US
dc.publisherJohn Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologistsen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.titleVitamin D and stress urinary incontinence in pregnancy: a cross-sectional studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.rights.holder© 2020 The Authors.en_US
dc.subject.nsiVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Gynekologi og obstetrikk: 756en_US
dc.source.journalBJOG: An International Journal of Obstetrics and Gynaecologyen_US

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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
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